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Jack Flanagan

Jack Flanagan

JackFlanagan,SeniorResearchFellowofUniversityofAuckland.JackFlanaganobtainedhisBSc(Hons)inBiochemistryandMolecularGeneticsatVictoriaUniversityofWellington,NewZealand,andwasawardedaPhDscholarshiptostudyattheJohnCurtinSchoolofMedicalResearch,AustralianNationalUniversity,AustraliawhereheinvestigatedstructurefunctionrelationshipsfortheglutathionetransferaseclassofdetoxicationenzymeinthelaboratoryofProfPhilipBoard.AfterapostdoctoralpositionresearchingstructurefunctionrelationshipsinthemajordrugmetabolisingcytochromesP450underProfRolandWolfattheBiomedicalResearchCentre,UniversityofDundee,UnitedKingdom,hetookupaHowardFloreyCentenaryFellowshipattheInstituteforMolecularBiosciences,UniversityofQueensland,AustralialookingatinhibitordiscoveryforthehumanhematopoieticprostaglandinD2synthaseenzyme.CurrentlyaSeniorResearchFellowattheAucklandCancerSocietyResearchCentre,Jackisinvolvedinintegratingmolecularmodellingandvirtualscreeningmethodsofinhibitordiscoveryintoanumberofcurrentmedicinalchemistryprojec

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详细介绍

Jack Flanagan, Senior Research Fellow of University of Auckland. Jack Flanagan obtained his BSc(Hons) in Biochemistry and Molecular Genetics at Victoria University of Wellington, New Zealand, and was awarded a PhD scholarship to study at the John Curtin School of Medical Research, Australian National University, Australia where he investigated structure function relationships for the glutathione transferase class of detoxication enzyme in the laboratory of Prof Philip Board. After a postdoctoral position researching structure function relationships in the major drug metabolising cytochromes P450 under Prof Roland Wolf at the Biomedical Research Centre, University of Dundee, United Kingdom, he took up a Howard Florey Centenary Fellowship at the Institute for Molecular Biosciences, University of Queensland, Australia looking at inhibitor discovery for the human hematopoietic prostaglandin D2 synthase enzyme. Currently a Senior Research Fellow at the Auckland Cancer Society Research Centre, Jack is involved in integrating molecular modelling and virtual screening methods of inhibitor discovery into a number of current medicinal chemistry projects. He is also an Associate Investigator in the Maurice Wilkins Centre for Molecular Biodiscovery.