Paul Teesdale-Spittle
PaulTeesdale-Spittle,ProfessorofVictoriaUniversityofWellington,LowerHutt,NewZealand.Hisresearchisprimarilyfocusedonthedesign,synthesisandevaluationofcompoundsforthetreatmentofcancerandparasiteinfection.Tothisend,hemakeuseofcomputationaltechniques(includingmolecularmodellingofligand-targetinteractionsandstructureactivityrelationshipanalysis),chemicalsynthesis(bysolutionandsolidphasetechniques,includingparallelcombinatorialsynthesis),andinvitroassays.CurrentprojectsinvolveinhibitorsofglutathioneS-transferaseenzymesasantiparasiticagents,pelorusideanditsanaloguesandbioreducibleanthraquinoneN-oxidetopoisomeraseinhibitorsasanticanceragents.HeisalsointerestedinunderstandingandharnessingWWdomains,whichareassociatedwithproteinrecognitionandbinding.