Pentao Liu
PentaoLiu,ProfessorofTheWellcomeTrustSangerInstitute,Cambridge,U.K.Dr.LiugraduatedfromHenanNormalUniversityandearnedhisMasterofSciencedegreefromChineseAcademyofSciences/UniversityofScienceandTechnologyofChina.AtBaylorCollegeofMedicine,hestudiedmolecularmechanismsofCharcoal-Marie-ToothdiseaseinDrJamesLupski'slaboratory.Dr.LiureceivedhisPhDfromBaylorCollegeofMedicineundertheguidanceofProfessorAllanBradley,andcompletedhispostdoctoraltrainingatNationalCancerInstitute(USA)inthelaboratoriesofDr.NealCopelandandDr.NancyJenkins.Dr.LiujoinedtheWellcomeTrustSangerInstituteinSeptember2003.Heinitiatedthehigh-throughputrecombineeringforthelarge-scalemousemutagenesisprogrammeattheSangerInstitute.Dr.Liu'slaboratoryhasidentifiedthecriticalrolesoftranscriptionfactors,Bcl11aandBcl11b,inhematopoieticstemcells,inlymphocytedevelopment,andinmammaryglanddevelopment.BymutatingBcl11b,theyhavediscoveredthatTlymphocytesarereprogrammedtoanewtypeofcancerkillercells,ITNKs.Dr.Liu'slabhasalsoidentifiedthatBCL11Aisanim